阴道菌群:2020年三大研究进展

2021-03-03 13:18 来源: 热心肠先生

Shotgun sequencing of the vaginal microbiome reveals both a species and functional potential signature of preterm birth

2020-11-12, doi: 10.1038/s41522-020-00162-8

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以上三个方面的研究都对阴道菌群领域做出了巨大的贡献,无论是阐明一个新的机制,还是发现一些新的生物标志物,或是检验候选产品的功效,这些研究都有助于改善女性的健康。

相信在未来的时间里,随着我们对阴道菌群的认知不断深入,我们将会开发出更多基于阴道菌群的疗法,更多的女性健康问题将会迎刃而解。

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参考文献:

1.Cohen CR, MR Wierzbicki, AL French, S Morris, S Newmann, H Reno, L Green, S Miller, J Powell, T Parks and A Hemmerling. (2020). Randomized Trial of Lactin-V to Prevent Recurrence of Bacterial Vaginosis. N Engl J Med 382:1906-1915.

2.Cheu RK, AT Gustin, C Lee, L Schifanella, CJ Miller, A Ha, C Kim, VJ Rodriguez, M Fischl, AD Burgener, KB Arnold, ML Alcaide and NR Klatt. (2020). Impact of vaginal microbiome communities on HIV antiretroviral-based pre-exposure prophylaxis (PrEP) drug metabolism. PLoS Pathog 16:e1009024.

3.Kosti I, S Lyalina, KS Pollard, AJ Butte and M Sirota. (2020). Meta-Analysis of Vaginal Microbiome Data Provides New Insights Into Preterm Birth. Front Microbiol 11:476.

4.Feehily C, D Crosby, CJ Walsh, EM Lawton, S Higgins, FM McAuliffe and PD Cotter. (2020). Shotgun sequencing of the vaginal microbiome reveals both a species and functional potential signature of preterm birth. NPJ Biofilms Microbiomes 6:50.

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