针对这一研究局限，Amy C. Justice教授提出了测量生物标志物的观点。“我们不会询问糖尿病患者他们的糖化血红蛋白水平如何，我们会检测这个指标……我们应该使用类似的（测量）方法就酒精风险向患者提供咨询。”比如，磷脂酰乙醇（phosphatidylethanol）是一种有潜力的直接反映饮酒状态的生物标志物，但磷脂酰乙醇仅在酒精暴露后28天内可检测到，如果能够随着时间推移重复测量磷脂酰乙醇，将提供有用、个体化的、准确的酒精暴露数据。

“我们越早开始准确测量酒精暴露量，我们就能越早了解可归因于酒精的真正的癌症负担并进行有效干预。”Amy C. Justice教授指出。

参考资料

[1] Rumgay H, et al., (2021). Global burden of cancer in 2020 attributable to alcohol consumption: a population-based study. Lancet Oncol, DOI: 10.1016/S1470-2045(21)00279-5

[2] Justice A, et al., (2021). Alcohol and the global burden of cancer: what are we missing. Lancet Oncol, DOI: 10.1016/S1470-2045(21)00329-6.

[3] List of Classifications. Retrieved July 14, 2021, from https://monographs.iarc.who.int/list-of-classifications

[4] The Lancet Onc.: Alcohol consumption linked to more than 740,000 new cancer cases in 2020. Retrieved July 14, 2021, from https://www.eurekalert.org/pub_releases/2021-07/tl-tlo071321.php

[5] Raise a Glass? Study Tallies Cancer Cases From Booze. Retrieved July 14, 2021, from https://www.medpagetoday.com/oncology/othercancers/93554

来源：健康界